Tuesday, November 24, 2015

The Embryological Development of Menisci

The embryological meniscal development seems to have an effect over the shaped the of the complete meniscal discoid and the incomplete meniscal discoid. Many studies investigated the shaped the of the complete meniscal discoid and the incomplete meniscal discoid. In one of the studies they were found to be the main causative factors of pain in the knee joint. The variations of the shape of the discoid menisci are explained by embryological meniscal development.


                                                                Complete discoid 
Embryological meniscal development
The meniscal arises from the differentiation of mesenchymal tissue within the limb bud by the eighth week of fetal development. During O’Rahilly stage 22, the menisci arises from the eccentric portions of the articular inter zone but it is not clearly noticeable until the ninth week of development.
            The blood supply during embryologic development enters from the periphery and continues throughout the entire width of each meniscus. However, the central third will receive blood supply by the ninth week after birth, and by adulthood, the peripheral one third is the only part that will be vascular. At the ninth week of the development there will be no more microscopic structural changes and the meniscus will grow at the same level as all the other intra-articular structures. By the fourteenth week the menisci will have a normal adult relationship with the other structures of the knee.


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